Zum Vorkommen Transmissibler Spongiformer Enzephalopathien beim Rehwild (Capreolus capreolus), Rotwild (Cervus elaphus) und Gamswild (Rupicapra rupicapra) in Bayern

Translated title of the contribution: Survey on Transmissible Spongiform Encephalopathies in Roe deer (Capreolus capreolus), Red deer (Cervus elaphus) and Chamois (Rupicapra rupicapra) in Bavaria

Karin Schwaiger, Birgit Stierstorfer, Wolfgang Schmahl, Johann Bauer

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Brain samples of 849 free-ranging ruminants (654 roe deer, 189 red deer and 6 chamois) from Bavaria were examined for TSE. In this respect, detections of PrP res were carried out by ELISA technique (BioRad) and immunohistochemistry using the monoclonal antibody (mAb) L42. Validation experiments of the ELISA technique for the detection of prionprotein from free-ranging ruminants showed that the examination of brains of wild ruminants lead to lower extinctions than that of bovine brain samples. Due to the fact that brain samples of 2 known CWD positive wapitis showed definite positive results, all samples were analysed by this test. There were no indications on the occurrence of TSE in any of the sample. In addition, immunohistochemical investigations of 10% of all samples did not show PrP res. Due to the large number of samples, the prevalence of TSE in Bavaria can be quoted under 0,5% for roe deer and under 1,5% for red deer with a certainty of 95%.

Translated title of the contributionSurvey on Transmissible Spongiform Encephalopathies in Roe deer (Capreolus capreolus), Red deer (Cervus elaphus) and Chamois (Rupicapra rupicapra) in Bavaria
Original languageGerman
Pages (from-to)24-29
Number of pages6
JournalBerliner und Munchener Tierarztliche Wochenschrift
Volume117
Issue number1-2
StatePublished - Jan 2004
Externally publishedYes

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