Zum Einfluß der alimentären Vitamin-BßVersorgung während Gravidität und Laktation auf die Aktivität spezifischer Transaminasen taktierender Ratten

Translated title of the contribution: Effect of dietary vitamin BO intake levels during gravidity and lactation on the activity of specific transaminases in lactating rats

D. A. Roth-Maier, J. Benedikt, M. Kirchgeßner

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Eighty female SpragueDawley rats weighing 257 g were fed during gravidity a semisynthetic diet containing five vitamin-Be-treatment groups (0.6, 3, 6, 18 and 180 mg/kg diet). The daily food intake was 14 g. During the following lactation the rats of each treatment group were divided into two groups containing 3 and 6 mg vitamin Be. At the 14th day of lactation the dams were decapitated. Parameters for determination of the vitamin-BoStatus were activity of AST and ALT in plasma, erythrocytes and liver. The average activity of AST in plasma was 549 U/l, in erythrocytes 1 939 U/l and liver 106 U/g fresh matter (FM). The increasing vitamin-Bo-Supplementation during gravidity resulted in an elevated activity of AST between lowest and highest treatment group in plasma 56 %, erythrocytes 44 %, and in liver 43 %, respectively. In response to the increasing vitamin-B6-treatment during lactation the activity of AST in plasma increased for 19 %, in erythrocytes for 13 %, and in liver for 24 %, respectively. A low vitamin-Bo-Supply (0.6 mg/kg diet) during gravidity in combination with demand-oriented supply during lactation (6 mg/kg diet) initiated the highest increase of activity. A deficient vitamin-BoSupply during lactation (3 mg/kg diet) could be compensated with optimal vitamin-Bo-Supply during gravidity. The values of ALT-activity showed no significant differences between the graded vitamin-Bo-Supplements, as a result of a high coenzyme saturation.

Translated title of the contributionEffect of dietary vitamin BO intake levels during gravidity and lactation on the activity of specific transaminases in lactating rats
Original languageGerman
Pages (from-to)282-287
Number of pages6
JournalZeitschrift fur Ernahrungswissenschaft
Volume35
Issue number3
DOIs
StatePublished - 1996

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