Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures

O. Seidl; C. Keller; H. Berger; G. Wolfram; N. Zöllner

doi:10.1016/0021-9150(83)90107-7

Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures

O. Seidl
, C. Keller
, H. Berger
, G. Wolfram
, N. Zöllner

Ludwig-Maximilians-Universität München

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.

Original language	English
Pages (from-to)	163-172
Number of pages	10
Journal	Atherosclerosis
Volume	46
Issue number	2
DOIs	https://doi.org/10.1016/0021-9150(83)90107-7
State	Published - Feb 1983
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Achilles tendon thickness
Coronary heart disease
Familial hypercholesterolemia
Fibroblast cultures in FHC
Xeroradiography

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10.1016/0021-9150(83)90107-7

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title = "Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures",

abstract = "Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.",

keywords = "Achilles tendon thickness, Coronary heart disease, Familial hypercholesterolemia, Fibroblast cultures in FHC, Xeroradiography",

author = "O. Seidl and C. Keller and H. Berger and G. Wolfram and N. Z{\"o}llner",

note = "Funding Information: The experimental work has been supported by a grant from the Deutsche Correspondence and reprint requests to: Dr. 0. Seidl, Medizinische Miinchen, Pettenkoferstrasse 8a, D-8000 Munich 2, F.R.G. * Dr. H. Berger, Klinik und Poliklinik fiir Radiologie, Ziemssenstrasse",

year = "1983",

month = feb,

doi = "10.1016/0021-9150(83)90107-7",

language = "English",

volume = "46",

pages = "163--172",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures

AU - Seidl, O.

AU - Keller, C.

AU - Berger, H.

AU - Wolfram, G.

AU - Zöllner, N.

N1 - Funding Information: The experimental work has been supported by a grant from the Deutsche Correspondence and reprint requests to: Dr. 0. Seidl, Medizinische Miinchen, Pettenkoferstrasse 8a, D-8000 Munich 2, F.R.G. * Dr. H. Berger, Klinik und Poliklinik fiir Radiologie, Ziemssenstrasse

PY - 1983/2

Y1 - 1983/2

N2 - Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.

AB - Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.

KW - Achilles tendon thickness

KW - Coronary heart disease

KW - Familial hypercholesterolemia

KW - Fibroblast cultures in FHC

KW - Xeroradiography

UR - https://www.scopus.com/pages/publications/0020660474

U2 - 10.1016/0021-9150(83)90107-7

DO - 10.1016/0021-9150(83)90107-7

M3 - Article

C2 - 6838697

AN - SCOPUS:0020660474

SN - 0021-9150

VL - 46

SP - 163

EP - 172

JO - Atherosclerosis

JF - Atherosclerosis

IS - 2

ER -

Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures

Abstract

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Keywords

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