X-ray phase radiography and tomography of soft tissue using grating interferometry

Timm Weitkamp, Christian David, Oliver Bunk, Jens Bruder, Peter Cloetens, Franz Pfeiffer

Research output: Contribution to journalArticlepeer-review

80 Scopus citations


X-ray phase and absorption radiographs and tomograms of the heart of a rat were taken with an X-ray grating interferometer with monochromatic synchrotron radiation at a photon energy of 17.5 keV. The phase images show largely superior quality with respect to the absorption images taken with the same dose, particularly much better contrast and contrast-to-noise ratio. Different tissues can clearly be distinguished. The results demonstrate the potential of grating interferometry for two- and three-dimensional X-ray imaging of biological soft tissue in an aqueous environment.

Original languageEnglish
Pages (from-to)S13-S17
JournalEuropean Journal of Radiology
Issue number3 SUPPL.
StatePublished - Dec 2008
Externally publishedYes


  • Radiography
  • Talbot interferometer
  • Tomography
  • X-ray interferometer
  • X-ray phase contrast


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