Workbench zur modellbildung, simulation und analyse zellulärer systeme

Andreas Kremling; Steffen Klamt; Martin Ginkel; Ernst Dieter Gilles

doi:10.1524/itit.46.1.12.26503

Workbench zur modellbildung, simulation und analyse zellulärer systeme

Translated title of the contribution: Workbench for model set up, simulation, and analysis of cellular systems

Andreas Kremling
, Steffen Klamt
, Martin Ginkel
, Ernst Dieter Gilles

Max Planck Institute for Dynamics of Complex Technical Systems

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Current research in molecular genetics and success in developing methods for functional genomics and proteomics lead to an unrivaled knowledge on biological systems. Tools that allow for a quantitative description and analysis become therefore more and more important. The paper at hand introduces tools for model set up, dynamical simulation and analysis. The tools were successfully applied for a number of biological model systems. Tool ProMoT supports the automatical generation of model equations; the equations were afterwards solved numerically with Diva. To analyze the structure of and to calculate flux distributions in metabolic networks, the FluxAnalyzer was developed.

Translated title of the contribution	Workbench for model set up, simulation, and analysis of cellular systems
Original language	German
Pages (from-to)	12-19
Number of pages	8
Journal	IT - Information Technology
Volume	46
Issue number	1
DOIs	https://doi.org/10.1524/itit.46.1.12.26503
State	Published - 1 Jan 2004
Externally published	Yes

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title = "Workbench zur modellbildung, simulation und analyse zellul{\"a}rer systeme",

abstract = "Current research in molecular genetics and success in developing methods for functional genomics and proteomics lead to an unrivaled knowledge on biological systems. Tools that allow for a quantitative description and analysis become therefore more and more important. The paper at hand introduces tools for model set up, dynamical simulation and analysis. The tools were successfully applied for a number of biological model systems. Tool ProMoT supports the automatical generation of model equations; the equations were afterwards solved numerically with Diva. To analyze the structure of and to calculate flux distributions in metabolic networks, the FluxAnalyzer was developed.",

keywords = "Cellular systems, J.3 [Life and Medical Science] Workbench",

author = "Andreas Kremling and Steffen Klamt and Martin Ginkel and Gilles, \{Ernst Dieter\}",

note = "Publisher Copyright: {\textcopyright} 2004 Oldenbourg Wissenschaftsverlag GmbH.",

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AU - Gilles, Ernst Dieter

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ER -

Workbench zur modellbildung, simulation und analyse zellulärer systeme

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