WIRKUNGSVERSTARKUNG VON NICHTDEPOLARISIERENDEN MUSKELRELAXANZIEN DURCH NIFEDIPIN I.V. IN INHALATIONSANAESTHESIE

Translated title of the contribution: Potentiation of nondepolarizing muscle relaxants by nifedipine during isoflurane anesthesia

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Abstract

Calcium entry blockers are now widely used in the treatment of cardiovascular diseases. Nifedipine is established for the treatment of perioperative hypertension during anesthesia. Previous animal experiments have demonstrated that calcium entry blockers potentiate the neuromuscular response induced by nondepolarizing blocking drugs. Occasional observations in patients have led to the suggestion that this phenomen may be of clinical significance. The interaction of nifedipine with nondepolarizing muscle relaxants in patients was assessed in a prospective clinical study.

Translated title of the contributionPotentiation of nondepolarizing muscle relaxants by nifedipine during isoflurane anesthesia
Original languageGerman
Pages (from-to)173-178
Number of pages6
JournalAnaesthesist
Volume39
Issue number3
StatePublished - 1990
Externally publishedYes

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