WERTIGKEIT HORMONELLER UND SONOGRAPHISCHER PARAMETER BEI DER DIAGNOSTIK DER GESTORTEN BZW. UNGESTORTEN FRUHGRAVIDITAT

Translated title of the contribution: The evaluation of hormonal and sonographic parameters in the diagnosis of normal and abnormal early pregnancy

R. Wiedemann, T. Strowitzki, R. Sandner, P. Luppa, H. Hepp

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

In 112 clinical pregnancies after IVF/ET or GIFT, the importance of β-HCG progesterone and 17 β-estradiol was evaluated. Additionally, we performed a vaginosonography to confirm an early intrauterine pregnancy. The aim of the study was to define, when a clinical pregnancy can be detected as early as possible and when the differential diagnosis of intact or abnormal pregnancy can be made. By measuring E2 in an HCG substituted cycle, the diagnosis of a clinical pregnancy is possible as soon as day +12 after induction of ovulation. When considering β-HCG levels alone, the same diagnosis can be made at day +18. Single determinations of HCG level do not offer a satisfactory diagnosis, because of intra-individual variations. A progesterone drop always demonstrates a disturbed early pregnancy. Using a combination of hormonal serial measurements of HCG, E2, progesterone and vaginosonography, the diagnosis of an intact intrauterine pregnancy should be possible as early as day +27 after ovulation induction.

Translated title of the contributionThe evaluation of hormonal and sonographic parameters in the diagnosis of normal and abnormal early pregnancy
Original languageGerman
Pages (from-to)237-242
Number of pages6
JournalGeburtshilfe und Frauenheilkunde
Volume49
Issue number3
DOIs
StatePublished - 1989
Externally publishedYes

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