Vorkommen von zearalenon, α- und β-zearalenol in gallen von zuchtsauen in relation zum fruchtbarkeitsgeschehen

Translated title of the contribution: Occurrence of zearalenone, α- and β-zearalenol in biles of breeding sows in relation to the reproductive performance

K. Meyer, E. Usleber, E. Martlbauer, J. Bauer

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Although zearalenone-induced reproductive disorders and the clinical appearance of hyperestrogenism were reproduced and documented quite often the role of zearalenone-contaminated fodder as a cause for fertility problems in sow breeding is still discussed controversial. Therefore the correlation of zearalenone and zearalenone-derivatives in bile (n = 794) and feed (n = 158) with fertility problems of unknown origin was investigated in this study. For the analysis of zearalenone and its derivatives in bile a HPLC/EIA combination was used. On the one hand, this procedure guaranteed the quantitatively reproducible detection, on the other hand, the investigation expenditure could be kept small with regard to a later effort in the routine diagnostics. The detection limits for zearalenone, α- and β-zearalenol in bile were at 1.0 ng/ml, 1.0 ng/ml, and 3.0 ng/ml, respectively. Results were confirmed by GC-MS. Zearalenone and zearalenone-derivatives were detected in almost every bile analysed. The contamination rate was 96.2 %. In opposition to recent investigations β-zearalenol was perceived as a relevant metabolite in swine. The contamination rate of feeding stuffs was 25.9 %. Incubation of samples with β-glucosidase did not elevate the detected amounts of zearalenone. As the measurable concentrations in bile and fodder were only slightly correlated the analysis of bile represents a reasonable alternative for fodder investigation. However, a correlation between the occurrence of zearalenone, α- and β-zearalenol in bile of sows and noninfectious reproductive disorders could not be established at the loading level found. These results are in line with those statements obtained in feeding experiments regarding the risk evaluation of zearalenone in sow reproduction.

Translated title of the contributionOccurrence of zearalenone, α- and β-zearalenol in biles of breeding sows in relation to the reproductive performance
Original languageGerman
Pages (from-to)374-379
Number of pages6
JournalBerliner und Munchener Tierarztliche Wochenschrift
Volume113
Issue number10
StatePublished - 2000
Externally publishedYes

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