Volumetric optoacoustic imaging with multi-bandwidth deconvolution

Andreas Buehler, X. Luis Dean-Ben, Daniel Razansky, Vasilis Ntziachristos

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Optoacoustic (photoacoustic) imaging based on cylindrically focused 1-D transducer arrays comes with powerful characteristics in visualizing optical contrast. Parallel reading of multiple detectors arranged around a tissue cross section enables capturing data for generating images of this plane within micro-seconds. Dedicated small animals scanners and handheld systems using 1-D cylindrically focused ultrasound transducer arrays have demonstrated real-time cross-sectional imaging and high in-plane resolution. Yet, the resolution achieved along the axis perpendicular to the focal plane, i.e., the elevation resolution, is determined by the focusing capacities of the detector and is typically lower than the in-plane resolution. Herein, we investigated whether deconvolution of the sensitivity field of the transducer could lead to tangible image improvements. We showcase the findings on experimental measurements from phantoms and animals and discuss the features and the limitations of the approach in improving resolution along the elevation dimension.

Original languageEnglish
Article number6600864
Pages (from-to)814-821
Number of pages8
JournalIEEE Transactions on Medical Imaging
Volume33
Issue number4
DOIs
StatePublished - Apr 2014

Keywords

  • Cross-sectional imaging
  • Three-dimensional (3-D) imaging
  • optoacoustic tomography
  • out-of-plane artefacts
  • photoacoustic tomography

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