Volume and shape preservation of enhancing lesions when applying non-rigid registration to a time series of contrast enhancing MR breast images

C. Tanner, J. A. Schnabel, D. Chung, M. J. Clarkson, D. Rueckert, D. L.G. Hill, D. J. Hawkes

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

69 Scopus citations

Abstract

In this paper we show first that a non-rigid registration algorithm used to register time-series MR images of the breast, can result in significant volume changes in the region of the enhanced lesion. Since this is physically implausible, given the short duration of the MR time series acquisition, the non-rigid registration algorithm was extended to allow the incorporation of rigid regions. In this way the registration is done in two stages. The enhanced lesions are first detected using the non-rigid registration algorithm in its original form. Secondly, the region of the enhanced lesion is set to be rigid and the new algorithm is applied to integrate this rigid region into the existing registration. By definition, volume and shape will be preserved in this rigid region. Preliminary results of applying this algorithm to 15 datasets are described.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2000 - 3rd International Conference, Proceedings
EditorsScott L. Delp, Anthony M. DiGoia, Branislav Jaramaz
PublisherSpringer Verlag
Pages327-337
Number of pages11
ISBN (Print)3540411895, 9783540411895
DOIs
StatePublished - 2000
Externally publishedYes
Event3rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2000 - Pittsburgh, United States
Duration: 11 Oct 200014 Oct 2000

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume1935
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference3rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2000
Country/TerritoryUnited States
CityPittsburgh
Period11/10/0014/10/00

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