Vitellogenin - A biomarker for endocrine disruptors

P. D. Hansen, H. Dizer, B. Hock, A. Marx, J. Sherry, M. McMaster, Ch Blaise

Research output: Contribution to journalShort surveypeer-review


This article describes the use of vitellogenin as a biomarker for endocrine disruption in fish. The lowest effective concentrations of vitellogenin are reported for oestrogenic compounds like 17β-oestradiol, nonylphenol and bisphenol A. Comparative studies of oestrogens detected in sewage plants from Germany and the UK are discussed. The article points out future directions in the application of vitellogenin ELISA assays and how these assays can provide additional information for a better understanding of the environmental behaviour of pollutants. Copyright (C) 1998 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)448-451
Number of pages4
JournalEuropean Journal of Pharmacology
Issue number2-3
StatePublished - 1999
Externally publishedYes


  • Endocrine disruption
  • Sewage plants
  • Trouts
  • Vitellogenin


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