Abstract
The human parvovirus B19 is the infective agent of erythema infectiosum. A number of other diseases such as aplastic anemia and arthritis may also be associated with parvovirus infections. Parenteral transmission is possible since recipients of clotting factors have a significantly higher prevalence of antibodies than the general population. The cytomegalovirus (CMV) can also be transmitted by blood transfusion. A special problem of CMV-transmission are patients receiving organ transplantats and immunosuppressive therapy. The Epstein-Barr virus (EBV) persists in B-lymphocytes after primary infection. Transfusion of blood, especially fresh blood, in EBV negative patients can result in EBV infection. The human immunodeficiency virus (HIV) is also transmitted by blood and blood products or intimate contact. By routine screening of blood units for antibodies against HIV-1 - and soon against the HIV-2 - these infections can be excluded with a high degree of probability. Heat inactivation of clotting factors can prevent transmission of HIV-1 and probably also of HIV-2 to hemophiliac patients.
| Translated title of the contribution | Viral infections transmitted by blood and blood products. Part 2: Parvovirus, CMV, EBV and HIV |
|---|---|
| Original language | German |
| Pages (from-to) | 184-186 |
| Number of pages | 3 |
| Journal | Fortschritte der Medizin |
| Volume | 105 |
| Issue number | 10 |
| State | Published - 1987 |
| Externally published | Yes |
