Versatile flexible graphene multielectrode arrays

Dmitry Kireev, Silke Seyock, Mathis Ernst, Vanessa Maybeck, Bernhard Wolfrum, Andreas Offenhäusser

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Graphene is a promising material possessing features relevant to bioelectronics applications. Graphene microelectrodes (GMEAs), which are fabricated in a dense array on a flexible polyimide substrate, were investigated in this work for their performance via electrical impedance spectroscopy. Biocompatibility and suitability of the GMEAs for extracellular recordings were tested by measuring electrical activities from acute heart tissue and cardiac muscle cells. The recordings show encouraging signal-to-noise ratios of 65 ± 15 for heart tissue recordings and 20 ± 10 for HL-1 cells. Considering the low noise and excellent robustness of the devices, the sensor arrays are suitable for diverse and biologically relevant applications.

Original languageEnglish
Article number1
JournalBiosensors
Volume7
Issue number1
DOIs
StatePublished - 23 Dec 2016

Keywords

  • Cell-graphene interface
  • Extracellular recordings
  • GMEA
  • Graphene
  • Graphene electrodes

Fingerprint

Dive into the research topics of 'Versatile flexible graphene multielectrode arrays'. Together they form a unique fingerprint.

Cite this