Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body

K. P. Siju; Vilim Štih; Sophie Aimon; Julijana Gjorgjieva; Ruben Portugues; Ilona C. Grunwald Kadow

doi:10.1016/j.cub.2020.04.037

Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body

K. P. Siju, Vilim Štih, Sophie Aimon, Julijana Gjorgjieva, Ruben Portugues, Ilona C. Grunwald Kadow

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Dopamine has been studied extensively in its role as a reward signal during learning across animal species. Taking advantage of the confined anatomy of DANs innervating the mushroom body (MB) of the fly, Siju et al. show that DAN populations encode innate odor and taste valence, movement, and physiological state in a MB-compartment-specific manner.

Original language	English
Pages (from-to)	2104-2115.e4
Journal	Current Biology
Volume	30
Issue number	11
DOIs	https://doi.org/10.1016/j.cub.2020.04.037
State	Published - 8 Jun 2020

Keywords

Drosophila
behavioral state
calcium imaging
dopamine
metabolic state
mushroom body
olfactory system
population coding
taste
valence

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10.1016/j.cub.2020.04.037

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title = "Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body",

abstract = "Dopamine has been studied extensively in its role as a reward signal during learning across animal species. Taking advantage of the confined anatomy of DANs innervating the mushroom body (MB) of the fly, Siju et al. show that DAN populations encode innate odor and taste valence, movement, and physiological state in a MB-compartment-specific manner.",

keywords = "Drosophila, behavioral state, calcium imaging, dopamine, metabolic state, mushroom body, olfactory system, population coding, taste, valence",

author = "Siju, {K. P.} and Vilim {\v S}tih and Sophie Aimon and Julijana Gjorgjieva and Ruben Portugues and {Grunwald Kadow}, {Ilona C.}",

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AU - Siju, K. P.

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AU - Aimon, Sophie

AU - Gjorgjieva, Julijana

AU - Portugues, Ruben

AU - Grunwald Kadow, Ilona C.

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KW - Drosophila

KW - behavioral state

KW - calcium imaging

KW - dopamine

KW - metabolic state

KW - mushroom body

KW - olfactory system

KW - population coding

KW - taste

KW - valence

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JO - Current Biology

JF - Current Biology

IS - 11

ER -

Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body

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Keywords

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