Unusual but reversible hepatic lesions following long-term treatment with pyridylcarbinol for familial hypercholesterolemia

C. Keller, W. Zoller, G. Wolfram, N. Zöllner

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We report two cases of unusual hepatic lesions following years of monotherapy with pyridylcarbinol (timespan) in a daily dose of 1.35 to 1.5 g for familial hypercholesterolemia. Mild elevations of liver enzymes correlated to a large tumorlike mass in the gallbladder region in one case and nodular changes in the whole liver (diagnosed by ultrasound) similar to metastatic lesions. After discontinuation of pyridylcarbinol the changes in the liver regressed markedly in both cases.

Original languageEnglish
Pages (from-to)647-650
Number of pages4
JournalKlinische Wochenschrift
Volume66
Issue number14
DOIs
StatePublished - Jul 1988
Externally publishedYes

Keywords

  • Familial Hypercholesterolemia
  • Liver enzymes
  • Pyridylcarbinol

Fingerprint

Dive into the research topics of 'Unusual but reversible hepatic lesions following long-term treatment with pyridylcarbinol for familial hypercholesterolemia'. Together they form a unique fingerprint.

Cite this