Untersuchungen zum einfluß eines niedermolekularen synthetischen huminstoffes auf ausgewählte reproduktionsparameter männlicher ratten

Translated title of the contribution: Influences of a low molecular humic substance (HS1500) on selected reproductive parameters in male rats

A. S. Faqi, N. Lange, M. Kühnert, A. Haase, H. Höke, B. Seubert

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Influences of the low molecular humic substance HS 1500 on parameters of organs (testis weight, epididymis weight), FSH-, and LH-levels in plasma as well as on the spermatogenesis of male rats were studied. After a daily oral application of 1000 mg/kg b.w. and 2000 mg/kg b.w., respectively over a period of 60 days (40th to 100th day of life) only 2 animals of the high dose group were observed with bilateral testicular atrophy. Despite of the two animals with testicular atrophy no significant differences between treated and control rats were observed with respect to testis morphology and spermatogenesis. There is no evidence whether the differences between the hormone levels and the testicular atrophy revealed is regarded to a HS 1500-effect or not. But otherwise a direct influence of HS 1500 can be ruled out with high certainty. Possibly because of the thin covering layer on the gastrointestinal mucous membrane formed by HS 1500, the absorption of nutritive substances is inhibited. Therefore the growth of sensitive organs like testis and epidymis, in the development period, can be decreased. Nevertheless, even after long time application the spermatogenesis is not influenced.

Translated title of the contributionInfluences of a low molecular humic substance (HS1500) on selected reproductive parameters in male rats
Original languageGerman
Pages (from-to)10-12
Number of pages3
JournalDeutsche Tierarztliche Wochenschrift
Volume103
Issue number1
StatePublished - 1996
Externally publishedYes

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