Unacylated ghrelin promotes skeletal muscle regeneration following hindlimb ischemia via SOD-2-mediated miR-221/222 expression.

Keyphrases

• Superoxide Dismutase 2 (SOD2) 100%
• MiR-221/222 100%
• Acylated Ghrelin 100%
• Skeletal muscle Regeneration 100%
• Hindlimb Ischemia 100%
• Ischemia 40%
• Reactive Oxygen Species 20%
• Tissue Damage 20%
• Myogenic 20%
• Mitogen 20%
• Satellite Cells 20%
• Peripheral Arterial Disease 20%
• P57Kip2 20%
• Mouse Model 10%
• Regenerative Process 10%
• Clinical Potential 10%
• Surgical Treatment 10%
• Antioxidant Effect 10%
• Ghrelin 10%
• Oxidative Stress 10%
• Post-transcriptional 10%
• Small Interfering RNA (siRNA) 10%
• Functional Impairment 10%
• Protein Kinase 10%
• Reoccurrence 10%
• Kinase Phosphorylation 10%
• CD68 10%
• Cell Injury 10%
• Cell Cycle Entry 10%
• Antioxidant Enzymes 10%
• Growth Hormone Secretagogue Receptor (GHS-R) 10%
• Muscle Regeneration 10%
• Skeletal muscle Damage 10%
• Protein Kinase Signaling 10%
• Pre-miR 10%
• Loss-of-function Experiments 10%

Neuroscience

• Skeletal Muscle 100%
• Ghrelin 100%
• Manganese Superoxide Dismutase 100%
• microRNA 221 100%
• Ischemia 100%
• Reactive Oxygen Species 18%
• Protein Kinases 18%
• Antioxidant 18%
• In Vivo 9%
• CD68 9%
• Cell Cycle 9%
• Oxidative Stress 9%
• Small Interfering RNA 9%
• Cell Damage 9%
• Receptor 9%

Immunology and Microbiology

• Skeletal Muscle 100%
• Muscle Regeneration 100%
• Superoxide Dismutase 100%
• Ghrelin 100%
• Mitogen 18%
• Artery 18%
• Satellite Cell 18%
• Mouse Model 9%
• CD68 9%
• Oxidative Stress 9%
• Cell Cycle 9%
• Cell Damage 9%