Ultraviolet A inhibits histamine release from human peripheral leukocytes

J. Ring; B. Przybilla; B. Eberlein

doi:10.1159/000234767

Ultraviolet A inhibits histamine release from human peripheral leukocytes

J. Ring, B. Przybilla, B. Eberlein

Ludwig-Maximilians-Universität München

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8 Scopus citations

Abstract

Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced-histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.

Original language	English
Pages (from-to)	136-138
Number of pages	3
Journal	International Archives of Allergy and Applied Immunology
Volume	88
Issue number	1-2
DOIs	https://doi.org/10.1159/000234767
State	Published - 1989
Externally published	Yes

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title = "Ultraviolet A inhibits histamine release from human peripheral leukocytes",

abstract = "Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced-histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.",

author = "J. Ring and B. Przybilla and B. Eberlein",

year = "1989",

doi = "10.1159/000234767",

language = "English",

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journal = "International Archives of Allergy and Applied Immunology",

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AU - Ring, J.

AU - Przybilla, B.

AU - Eberlein, B.

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N2 - Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced-histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.

AB - Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced-histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.

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JO - International Archives of Allergy and Applied Immunology

JF - International Archives of Allergy and Applied Immunology

IS - 1-2

ER -

Ultraviolet A inhibits histamine release from human peripheral leukocytes

Abstract

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