Ultraviolet A inhibits histamine release from human peripheral leukocytes

J. Ring, B. Przybilla, B. Eberlein

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced-histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.

Original languageEnglish
Pages (from-to)136-138
Number of pages3
JournalInternational Archives of Allergy and Applied Immunology
Issue number1-2
StatePublished - 1989
Externally publishedYes


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