Ultra-small angle neutron scattering and X-ray tomography studies of caseinate-hydroxyapatite microporous materials

C. Ritzoulis; M. Strobl; C. Panayiotou; G. Choinka; C. Tsioptsias; C. Vasiliadou; V. Vasilakos; F. Beckmann; J. Herzen; T. Donath

doi:10.1016/j.matchemphys.2010.03.064

Ultra-small angle neutron scattering and X-ray tomography studies of caseinate-hydroxyapatite microporous materials

C. Ritzoulis
, M. Strobl
, C. Panayiotou
, G. Choinka
, C. Tsioptsias
, C. Vasiliadou
, V. Vasilakos
, F. Beckmann
, J. Herzen
, T. Donath

Alexander Technological Educational Institution
Heidelberg University
Helmholtz-Zentrum Berlin für Materialien und Energie (HZB)
Aristotle University of Thessaloniki
KEPAMAH
University of Crete
Helmholtz-Zentrum Hereon outstation at Heinz Maier-Leibnitz Zentrum (MLZ)

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Microporous hydroxyapatite-protein composite materials of bimodal pore size distribution, intended for utilization as bone regeneration scaffolds, have been prepared by means of milk caseinate emulsion droplet templating. Ultra-small angle neutron scattering (USANS) has been utilized in order to obtain information on the size distribution of the smaller pores (less than tens of micrometers), as compared to the emulsions that have been initially used as templates. The samples were subsequently visualized in 3 dimensions using synchrotron radiation X-ray tomography, where information concerning the larger pores has been obtained. The examination of the samples confirmed a strong correlation between the size of the templating droplets and the produced pores. In addition, 1 μm-sized pores appear to adhere to the surface of 20-70 μm pores, providing an irregular surface on the large pore walls, a desirable feature in bone-mimicking materials.

Original language	English
Pages (from-to)	77-82
Number of pages	6
Journal	Materials Chemistry and Physics
Volume	123
Issue number	1
DOIs	https://doi.org/10.1016/j.matchemphys.2010.03.064
State	Published - 1 Sep 2010
Externally published	Yes

Keywords

Microporous materials
Microstructure
Neutron scattering and diffraction
X-ray tomography

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10.1016/j.matchemphys.2010.03.064

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title = "Ultra-small angle neutron scattering and X-ray tomography studies of caseinate-hydroxyapatite microporous materials",

abstract = "Microporous hydroxyapatite-protein composite materials of bimodal pore size distribution, intended for utilization as bone regeneration scaffolds, have been prepared by means of milk caseinate emulsion droplet templating. Ultra-small angle neutron scattering (USANS) has been utilized in order to obtain information on the size distribution of the smaller pores (less than tens of micrometers), as compared to the emulsions that have been initially used as templates. The samples were subsequently visualized in 3 dimensions using synchrotron radiation X-ray tomography, where information concerning the larger pores has been obtained. The examination of the samples confirmed a strong correlation between the size of the templating droplets and the produced pores. In addition, 1 μm-sized pores appear to adhere to the surface of 20-70 μm pores, providing an irregular surface on the large pore walls, a desirable feature in bone-mimicking materials.",

keywords = "Microporous materials, Microstructure, Neutron scattering and diffraction, X-ray tomography",

author = "C. Ritzoulis and M. Strobl and C. Panayiotou and G. Choinka and C. Tsioptsias and C. Vasiliadou and V. Vasilakos and F. Beckmann and J. Herzen and T. Donath",

year = "2010",

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doi = "10.1016/j.matchemphys.2010.03.064",

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T1 - Ultra-small angle neutron scattering and X-ray tomography studies of caseinate-hydroxyapatite microporous materials

AU - Ritzoulis, C.

AU - Strobl, M.

AU - Panayiotou, C.

AU - Choinka, G.

AU - Tsioptsias, C.

AU - Vasiliadou, C.

AU - Vasilakos, V.

AU - Beckmann, F.

AU - Herzen, J.

AU - Donath, T.

PY - 2010/9/1

Y1 - 2010/9/1

N2 - Microporous hydroxyapatite-protein composite materials of bimodal pore size distribution, intended for utilization as bone regeneration scaffolds, have been prepared by means of milk caseinate emulsion droplet templating. Ultra-small angle neutron scattering (USANS) has been utilized in order to obtain information on the size distribution of the smaller pores (less than tens of micrometers), as compared to the emulsions that have been initially used as templates. The samples were subsequently visualized in 3 dimensions using synchrotron radiation X-ray tomography, where information concerning the larger pores has been obtained. The examination of the samples confirmed a strong correlation between the size of the templating droplets and the produced pores. In addition, 1 μm-sized pores appear to adhere to the surface of 20-70 μm pores, providing an irregular surface on the large pore walls, a desirable feature in bone-mimicking materials.

AB - Microporous hydroxyapatite-protein composite materials of bimodal pore size distribution, intended for utilization as bone regeneration scaffolds, have been prepared by means of milk caseinate emulsion droplet templating. Ultra-small angle neutron scattering (USANS) has been utilized in order to obtain information on the size distribution of the smaller pores (less than tens of micrometers), as compared to the emulsions that have been initially used as templates. The samples were subsequently visualized in 3 dimensions using synchrotron radiation X-ray tomography, where information concerning the larger pores has been obtained. The examination of the samples confirmed a strong correlation between the size of the templating droplets and the produced pores. In addition, 1 μm-sized pores appear to adhere to the surface of 20-70 μm pores, providing an irregular surface on the large pore walls, a desirable feature in bone-mimicking materials.

KW - Microporous materials

KW - Microstructure

KW - Neutron scattering and diffraction

KW - X-ray tomography

UR - https://www.scopus.com/pages/publications/77953325844

U2 - 10.1016/j.matchemphys.2010.03.064

DO - 10.1016/j.matchemphys.2010.03.064

M3 - Article

AN - SCOPUS:77953325844

SN - 0254-0584

VL - 123

SP - 77

EP - 82

JO - Materials Chemistry and Physics

JF - Materials Chemistry and Physics

IS - 1

ER -

Ultra-small angle neutron scattering and X-ray tomography studies of caseinate-hydroxyapatite microporous materials

Abstract

Keywords

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