Two‐dimensional polyacrylamide gel electrophoresis with immobilized pH gradients in the first dimensin (IPG‐Dalt): The state of the art and the controversy of vertical versus horizontal systems

Angelika Görg, GÜNther Boguth, Christian Obermaier, Anton Posch, Walter Weiss

Research output: Contribution to journalArticlepeer-review

233 Scopus citations

Abstract

After having established the basic protocol of two‐dimensional electrophoresis with immobilized pH gradients in the first dimension (IPG‐Dalt) in 1988 (A. Görg et al., Electrophoresis 1988, 9, 531–546), some critical parameters of the actual IPG‐Dalt protocols as well as the results obtained with horizontal and vertical second‐dimensional sodium dodecyl sulfate‐electrophoresis are demonstrated and discussed.

Original languageEnglish
Pages (from-to)1079-1086
Number of pages8
JournalELECTROPHORESIS
Volume16
Issue number1
DOIs
StatePublished - 1995

Keywords

  • Immobilized pH gradients
  • Two‐dimensional polyacrylamide gel electrophoresis

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