Tratamientos acupunturales para el dolor: una revisión sistemática de ensayos clínicos aleatorizados con grupos de acupuntura, acupuntura placebo y no acupunturales

Translated title of the contribution: Acupuncture treatments for pain: A systematic review of randomized clinical trials with acupuncture groups, placebo acupuncture and no acupuncture

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To study the analgesic effect of acupuncture and placebo acupuncture and to explore whether the type of the placebo acupuncture is associated with the estimated effect of acupuncture. Data sources: Cochrane Library, Medline, Embase, Biological Abstracts, and PsycLIT. Study selection: Three armed randomised clinical trials (including both a placebo or sham acupuncture group and a group receiving no acupuncture). Data extraction: Standardised mean differences from each trial were used to estimate the effect of acupuncture and placebo acupuncture. The different types of placebo acupuncture were ranked from 1 to 5 according to assessment of the possibility of a physiological effect, and this ranking was meta-regressed with the effect of acupuncture. Main results: Thirteen trials (3,025 patients) involving a variety of pain conditions were eligible. The allocation of patients was adequately concealed in eight trials. The clinicians managing the acupuncture and placebo acupuncture treatments were not blinded in any of the trials. One clearly outlying trial (70 patients) was excluded. A small difference was found between acupuncture and placebo acupuncture: standardised mean difference -0.17 (95% confidence interval -0.26 to -0.08), corresponding to 4 mm (2 mm to 6 mm) on a 100 mm visual analogue scale. No statistically significant heterogeneity was present (P = 0.10, I2 = 36%). A moderate difference was found between placebo acupuncture and no acupuncture: standardised mean difference -0.42 (-0.60 to -0.23). However, considerable heterogeneity (P < 0.001, I2 = 66%) was also found, as large trials reported both small and large effects of placebo. No association was detected between the type of placebo acupuncture and the effect of acupuncture (P = 0.60). Conclusion: A small analgesic effect of acupuncture was found, which seems to lack clinical relevance and cannot be clearly distinguished from bias. Whether needling at acupuncture points, or at any site, reduces pain independently of the psychological impact of the treatment ritual is unclear.

Translated title of the contributionAcupuncture treatments for pain: A systematic review of randomized clinical trials with acupuncture groups, placebo acupuncture and no acupuncture
Original languageSpanish
Pages (from-to)148-149
Number of pages2
JournalRevista Internacional de Acupuntura
Volume4
Issue number3
DOIs
StatePublished - 2010
Externally publishedYes

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