Transition metal ion-catalysed oxygen activation during pathogenic processes

Susanne Hippeli; Erich F. Elstner

doi:10.1016/S0014-5793(98)01665-2

Transition metal ion-catalysed oxygen activation during pathogenic processes

Susanne Hippeli, Erich F. Elstner

Life Sciences

Technical University of Munich

Research output: Contribution to journal › Review article › peer-review

132 Scopus citations

Abstract

Most pathological processes include the production of activated oxygen species augmented or attenuated by transition metal ions catalyzing one electron transitions. Inhalation of airborne particles, infections, ingestion of toxins or liberation from endogenous stores represent biological pathways for the induction of pathogenic processes by these metal ions. In this short review basic reactions involving transition metal ions operating during oxidative stress in certain diseases will be discussed.

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	FEBS Letters
Volume	443
Issue number	1
DOIs	https://doi.org/10.1016/S0014-5793(98)01665-2
State	Published - 22 Jan 1999

Keywords

Disease
Radical chain reaction
Reactive oxygen species
Transition metal ion

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10.1016/S0014-5793(98)01665-2

Cite this

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abstract = "Most pathological processes include the production of activated oxygen species augmented or attenuated by transition metal ions catalyzing one electron transitions. Inhalation of airborne particles, infections, ingestion of toxins or liberation from endogenous stores represent biological pathways for the induction of pathogenic processes by these metal ions. In this short review basic reactions involving transition metal ions operating during oxidative stress in certain diseases will be discussed.",

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AU - Elstner, Erich F.

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AB - Most pathological processes include the production of activated oxygen species augmented or attenuated by transition metal ions catalyzing one electron transitions. Inhalation of airborne particles, infections, ingestion of toxins or liberation from endogenous stores represent biological pathways for the induction of pathogenic processes by these metal ions. In this short review basic reactions involving transition metal ions operating during oxidative stress in certain diseases will be discussed.

KW - Disease

KW - Radical chain reaction

KW - Reactive oxygen species

KW - Transition metal ion

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Transition metal ion-catalysed oxygen activation during pathogenic processes

Abstract

Keywords

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