Transfer learning of tissue photon interaction in optical coherence tomography towardsin vivo histology of the oral mucosa

Debdoot Sheet, Satarupa Banerjee, Sri Phani Krishna Karri, Swarnendu Bag, Anji Anura, Amita Giri, Ranjan Rashmi Paul, Mousumi Pal, Badal C. Sarkar, Ranjan Ghosh, Amin Katouzian, Nassir Navab, Ajoy K. Ray

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

Oral cancer evolves from different premalignant conditions and the key to save lives is through diagnosis of early symptoms. The conventional practice of post biopsy histopathol-ogy reporting is dependent on specificity of sampling site and optical coherence tomography (OCT) imaging is clinically used for guidance. Clinicians infer the tissue constitution by interpreting intensity images and are challenged by interand intra-observer variability. In this paper we propose transfer learning of tissue specific photon interaction statistical physics in swept-source OCT for characterizing the oral mu-cosa with the aim of reducing this reporting variability. The source task models statistical physics of ballistic and near-ballistic photons and its intensity attenuation and target task learns the parameters obtained by solving the source task to identify co-located heterogeneity of tissues. Performance is compared with conventional histopathology of healthy, premalignant and malignant oral lesions supporting its use towards in vivo histology of the oral mucosa for pre-biopsy screening.

Original languageEnglish
Title of host publication2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1389-1392
Number of pages4
ISBN (Electronic)9781467319591
DOIs
StatePublished - 29 Jul 2014
Event2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China
Duration: 29 Apr 20142 May 2014

Publication series

Name2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

Conference

Conference2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
Country/TerritoryChina
CityBeijing
Period29/04/142/05/14

Keywords

  • In vivo histology
  • Optical coherence tomography
  • Oral cancer
  • Tissue characterization
  • Transfer learning

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