TY - JOUR
T1 - Transcription factor BES1 interacts with HSFA1 to promote heat stress resistance of plants
AU - Albertos, Pablo
AU - Dündar, Gönül
AU - Schenk, Philipp
AU - Carrera, Sergio
AU - Cavelius, Philipp
AU - Sieberer, Tobias
AU - Poppenberger, Brigitte
N1 - Publisher Copyright:
© 2021 The Authors Published under the terms of the CC BY NC ND 4.0 license
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Heat stress is a major environmental stress type that can limit plant growth and development. To survive sudden temperature increases, plants utilize the heat shock response, an ancient signaling pathway. Initial results had suggested a role for brassinosteroids (BRs) in this response. Brassinosteroids are growth-promoting steroid hormones whose activity is mediated by transcription factors of the BES1/BZR1 subfamily. Here, we provide evidence that BES1 can contribute to heat stress signaling. In response to heat, BES1 is activated even in the absence of BRs and directly binds to heat shock elements (HSEs), known binding sites of heat shock transcription factors (HSFs). HSFs of the HSFA1 type can interact with BES1 and facilitate its activity in HSE binding. These findings lead us to propose an extended model of the heat stress response in plants, in which the recruitment of BES1 is a means of heat stress signaling cross-talk with a central growth regulatory pathway.
AB - Heat stress is a major environmental stress type that can limit plant growth and development. To survive sudden temperature increases, plants utilize the heat shock response, an ancient signaling pathway. Initial results had suggested a role for brassinosteroids (BRs) in this response. Brassinosteroids are growth-promoting steroid hormones whose activity is mediated by transcription factors of the BES1/BZR1 subfamily. Here, we provide evidence that BES1 can contribute to heat stress signaling. In response to heat, BES1 is activated even in the absence of BRs and directly binds to heat shock elements (HSEs), known binding sites of heat shock transcription factors (HSFs). HSFs of the HSFA1 type can interact with BES1 and facilitate its activity in HSE binding. These findings lead us to propose an extended model of the heat stress response in plants, in which the recruitment of BES1 is a means of heat stress signaling cross-talk with a central growth regulatory pathway.
UR - http://www.scopus.com/inward/record.url?scp=85122177560&partnerID=8YFLogxK
U2 - 10.15252/embj.2021108664
DO - 10.15252/embj.2021108664
M3 - Article
C2 - 34981847
AN - SCOPUS:85122177560
SN - 0261-4189
VL - 41
JO - EMBO Journal
JF - EMBO Journal
IS - 3
M1 - e108664
ER -