Transcranial imaging with the optoacoustic memory effect

Xosé Luís Deán-Ben, Daniel Razansky

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Severe distortion of ultrasound waves traversing the skull impedes visualization of cerebral structures in humans. Accurate modelling of ultrasound propagation effects is challenging due to highly heterogeneous acoustic properties of the skull bone. Here we demonstrate that acoustic distortions induced by the skull are preserved for optoacoustic waves generated at neighboring point sources. This memory effect is exploited for building a model describing generation and detection of a signal originating from light-absorbing particle at given position. Model-based inversion is shown to accurately recover the absorption distribution with comparable spatial resolution to that obtained without the presence of the skull.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2022
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510647916
DOIs
StatePublished - 2022
Externally publishedYes
EventPhotons Plus Ultrasound: Imaging and Sensing 2022 - Virtual, Online
Duration: 20 Feb 202224 Feb 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11960
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2022
CityVirtual, Online
Period20/02/2224/02/22

Keywords

  • Memory Effect
  • Model-based Reconstruction
  • Optoacoustic Imaging
  • Photoacoustic Imaging
  • Skull

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