Transcranial Doppler sonography in the differential diagnosis of Alzheimer's disease and multi-infarct dementia

S. Biedert, H. Forstl, W. Hewer

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We have investigated the blood flow velocity profiles of the basal cerebral arteries by means of transcranial Doppler sonography in patients with primary degnerative dementia of the Alzheimer type and those with multi-infarct dementia. While the blood flow velocities in middle cerebral and basilar arteries reveal no clearcut differences between the patient subsets and their age-matched controls, a statistically significant decrease of the relative end-diastolic flow velocity (modified Pourcelot index) was found only in patients with multi-infarct dementia. Thus, if the modified Pourcelot index in all major cerebral arteries is significantly reduced with respect to age-matched controls, it may be used as an additional criterion of a multi-infarct syndrome in demented patients.

Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalJournal of Cardiovascular Technology
Volume9
Issue number2
StatePublished - 1990
Externally publishedYes

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