Towards easy-to-use bacteria sensing: Modeling and simulation of a new environmental impedimetric biosensor in fluids

Christian Pfeffer, Yue Liang, Helmut Grothe, Bernhard Wolf, Ralf Brederlow

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Conventional pathogenic bacteria-detection methods are lab-bound, time-consuming and need trained personnel. Microelectrodes can be used to recognize harmful microorganisms by dielectric impedance spectroscopy. However, crucial for this spectroscopy method are the spatial dimensions and layout of the electrodes, as the corresponding distribution of the electric field defines the sensor system parameters such as sensitivity, SNR, and dynamic range. Therefore, a variety of sensor models are created and evaluated. FEM simulations in 2D and 3D are conducted for this impedimetric sensor. The authors tested differently shaped structures, verified the linear influence of the excitation amplitude and developed a mathematical concept for a quality factor that practically allows us to distinguish arbitrary sensor designs and layouts. The effect of guard electrodes blocking outer influences on the electric field are investigated, and essential configurations are explored. The results lead to optimized electronic sensors in terms of geometrical dimensions. Possible material choices for real sensors as well as design and layout recommendations are presented.

Original languageEnglish
Article number1487
Pages (from-to)1-13
Number of pages13
JournalSensors (Switzerland)
Volume21
Issue number4
DOIs
StatePublished - 2 Feb 2021

Keywords

  • Bacteria detection
  • Bacteria sensor
  • Biosensor
  • Electrochemical sensor
  • FEM simulation
  • Impedance spectroscopy
  • Pathogens
  • Sensor design

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