TY - GEN
T1 - Towards 3D registration of fetal brain MRI and ultrasound
AU - Kuklisova-Murgasova, Maria
AU - Quaghebeur, Gerardine
AU - Hajnal, Joseph V.
AU - Noble, J. Alison
AU - Schnabel, Julia A.
PY - 2012
Y1 - 2012
N2 - We propose a novel method for automatic alignment of fetal brain magnetic resonance image volumes and 3D ultrasound images. Volumetric fetal brain MRI is obtained from reconstructing 2D slices, and is then segmented using a preterm neonatal probabilistic atlas. The segmentation is further refined to extract features that are prominent in fetal brain ultrasound. From the MR segmentation, a pseudo-ultrasound image is simulated, taking into account the direction of the beam in the real ultrasound volume. The simulated and real ultrasound images are then affinely aligned using normalized cross-correlation. We show that the proposed approach performs better than the standard approach for multi-modal registration of the MR and ultrasound volumes driven by normalized mutual information.
AB - We propose a novel method for automatic alignment of fetal brain magnetic resonance image volumes and 3D ultrasound images. Volumetric fetal brain MRI is obtained from reconstructing 2D slices, and is then segmented using a preterm neonatal probabilistic atlas. The segmentation is further refined to extract features that are prominent in fetal brain ultrasound. From the MR segmentation, a pseudo-ultrasound image is simulated, taking into account the direction of the beam in the real ultrasound volume. The simulated and real ultrasound images are then affinely aligned using normalized cross-correlation. We show that the proposed approach performs better than the standard approach for multi-modal registration of the MR and ultrasound volumes driven by normalized mutual information.
KW - 3D ultrasound
KW - Fetal brain imaging
KW - MRI
KW - multimodal registration
UR - https://www.scopus.com/pages/publications/84864836911
U2 - 10.1109/ISBI.2012.6235555
DO - 10.1109/ISBI.2012.6235555
M3 - Conference contribution
AN - SCOPUS:84864836911
SN - 9781457718588
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 346
EP - 349
BT - 2012 9th IEEE International Symposium on Biomedical Imaging
PB - IEEE Computer Society
T2 - 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012
Y2 - 2 May 2012 through 5 May 2012
ER -