Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Michael Helou; Mathias Reisbeck; Sandro F. Tedde; Lukas Richter; Ludwig Bär; Jacobus J. Bosch; Roland H. Stauber; Eckhard Quandt; Oliver Hayden

doi:10.1039/c3lc41310a

Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Michael Helou
, Mathias Reisbeck
, Sandro F. Tedde
, Lukas Richter
, Ludwig Bär
, Jacobus J. Bosch
, Roland H. Stauber
, Eckhard Quandt
, Oliver Hayden

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

Original language	English
Pages (from-to)	1035-1038
Number of pages	4
Journal	Lab on a Chip
Volume	13
Issue number	6
DOIs	https://doi.org/10.1039/c3lc41310a
State	Published - 21 Mar 2013
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/c3lc41310a

Cite this

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title = "Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation",

abstract = "Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.",

author = "Michael Helou and Mathias Reisbeck and Tedde, \{Sandro F.\} and Lukas Richter and Ludwig B{\"a}r and Bosch, \{Jacobus J.\} and Stauber, \{Roland H.\} and Eckhard Quandt and Oliver Hayden",

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AU - Helou, Michael

AU - Reisbeck, Mathias

AU - Tedde, Sandro F.

AU - Richter, Lukas

AU - Bär, Ludwig

AU - Bosch, Jacobus J.

AU - Stauber, Roland H.

AU - Quandt, Eckhard

AU - Hayden, Oliver

PY - 2013/3/21

Y1 - 2013/3/21

N2 - Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

AB - Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

UR - https://www.scopus.com/pages/publications/84875852339

U2 - 10.1039/c3lc41310a

DO - 10.1039/c3lc41310a

M3 - Article

AN - SCOPUS:84875852339

SN - 1473-0197

VL - 13

SP - 1035

EP - 1038

JO - Lab on a Chip

JF - Lab on a Chip

IS - 6

ER -

Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Abstract

UN SDGs

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