Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Michael Helou, Mathias Reisbeck, Sandro F. Tedde, Lukas Richter, Ludwig Bär, Jacobus J. Bosch, Roland H. Stauber, Eckhard Quandt, Oliver Hayden

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

Original languageEnglish
Pages (from-to)1035-1038
Number of pages4
JournalLab on a Chip
Volume13
Issue number6
DOIs
StatePublished - 21 Mar 2013
Externally publishedYes

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