Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Michael Helou; Mathias Reisbeck; Sandro F. Tedde; Lukas Richter; Ludwig Bär; Jacobus J. Bosch; Roland H. Stauber; Eckhard Quandt; Oliver Hayden

doi:10.1039/c3lc41310a

Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Michael Helou, Mathias Reisbeck, Sandro F. Tedde, Lukas Richter, Ludwig Bär, Jacobus J. Bosch, Roland H. Stauber, Eckhard Quandt, Oliver Hayden

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

Original language	English
Pages (from-to)	1035-1038
Number of pages	4
Journal	Lab on a Chip
Volume	13
Issue number	6
DOIs	https://doi.org/10.1039/c3lc41310a
State	Published - 21 Mar 2013
Externally published	Yes

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10.1039/c3lc41310a

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abstract = "Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.",

author = "Michael Helou and Mathias Reisbeck and Tedde, {Sandro F.} and Lukas Richter and Ludwig B{\"a}r and Bosch, {Jacobus J.} and Stauber, {Roland H.} and Eckhard Quandt and Oliver Hayden",

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AU - Helou, Michael

AU - Reisbeck, Mathias

AU - Tedde, Sandro F.

AU - Richter, Lukas

AU - Bär, Ludwig

AU - Bosch, Jacobus J.

AU - Stauber, Roland H.

AU - Quandt, Eckhard

AU - Hayden, Oliver

PY - 2013/3/21

Y1 - 2013/3/21

N2 - Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

AB - Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

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DO - 10.1039/c3lc41310a

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Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

Abstract

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