Abstract
In response to their alleged 'uterus affinity' the organotropism of various Toxoplasma strains was investigated in the female mouse. Using quantitative histological (immunofluorescence) and seriological (Sabin-Feldman-dye test, complement fixation test), we examined the brain, heart, lung, spleen, striated muscle, uterus and ovaries. The following results were obtained: All four of the Toxoplasma strains (ALT, DX, WEISS, GAIL) showed a definite neurotropism. Located in the brain were 100 times as many cysts as in the sexual organs and 10 times as many as in the remaining organs. The uterus and ovary show a low susceptibility, invasion rarely occurring. An 'uterus affinity' could not be confirmed. All four Toxoplasma strains showed the same affinity for the various organs. The strain ALT showed the most virulence and formed the most cysts.
| Translated title of the contribution | Experimental studies on the affinity of Toxoplasma gondii to various organs of mice |
|---|---|
| Original language | German |
| Pages (from-to) | 565-571 |
| Number of pages | 7 |
| Journal | Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A |
| Volume | 242 |
| Issue number | 4 |
| State | Published - 1978 |