Three-component reactions of α- and β-bromo aldehydes with amides and dienophiles - An easy way to versatile 1-amido-2-cyclo hexenes

Sandra Hübner, Helfried Neumann, Dirk Michalik, Stefan Klaus, Dirk Strübing, Anke Spannenberg, Axel Jacobi Von Wangelin, Matthias Beller

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The scope of the three-component reaction of aldehydes, amides, and dienophiles, the so-called AAD reaction, is extended to the formation of 2- and 3-bromo-substituted 1-amido-2-cyclohexene derivatives. The incorporation of the halogen substituent allows further elaboration of this interesting class of products.

Original languageEnglish
Pages (from-to)1085-1090
Number of pages6
JournalSynlett
Issue number7
DOIs
StatePublished - 24 Apr 2007
Externally publishedYes

Keywords

  • Amides
  • Diels-Alder reaction
  • Dienophiles
  • Halogenated aldehydes
  • Multicomponent reaction

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