Thieme chemistry journal awardees - Where are they now? aldol synthesis by anti-markovnikov hydration of propargyloxy substrates: Feasibility, stereospecifity, and reiterative alkynylation-hydration

Lukas Hintermann, Thomas Kribber, Aurélie Labonne, Eva Paciok

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Aldol derivatives have been synthesized by redox-neutral catalytic anti-Markovnikov hydration of propargyloxy sub-strates. A reiterative sequence of aldehyde alkynylation and alkyne hydration leads to 1,3-polyol derivatives.

Original languageEnglish
Pages (from-to)2412-2416
Number of pages5
JournalSynlett
Issue number15
DOIs
StatePublished - Sep 2009
Externally publishedYes

Keywords

  • Addition reactions
  • Aldehydes
  • Alkynes
  • Homogeneous catalysis
  • Ruthenium

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