The treatment of hypercholesterolemia with beta-pyridylcarbinol. Part 5. Report on 16 Cases with Severe Hypercholesterolemia Treated for 12 Years

N. Zöllner, Ch Keller, G. Wolfram

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Abstract

A group of 78 patients with severe hypercholesterolemia (x = 464 mg/dl) and symptoms of vascular disease of the heart, the extremities, or the brain, started a beta-pyridylcarbinol treatment with an average daily dosage of 1.2 g in 1964. In 1976 we could re-examine 12 patients, still on the same therapy. No myocardial infarction has occurred in this group since 1973, only 2 patients have had more attacks of angina pectoris than 1964. In contrast patients discontinuing therapy or replacing beta-pyridylcarbinol by other hypolipidemic drugs had a higher mortality.

Original languageEnglish
Pages (from-to)611-615
Number of pages5
JournalAtherosclerosis
Volume26
Issue number4
DOIs
StatePublished - Apr 1977
Externally publishedYes

Keywords

  • Beta pyridylcarbinol
  • Hypercholesterolemia
  • Long-term treatment
  • Serum cholesterol levels

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