The photoinduced cleavage of coumarin dimers studied with femtosecond and nanosecond two-photon excitation

T. Buckup; J. Dorn; J. Hauer; S. Härtner; N. Hampp; M. Motzkus

doi:10.1016/j.cplett.2007.03.076

The photoinduced cleavage of coumarin dimers studied with femtosecond and nanosecond two-photon excitation

T. Buckup, J. Dorn, J. Hauer, S. Härtner, N. Hampp, M. Motzkus

Philipps-Universität Marburg

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The photocleavage of a coumarin derivative dimer is a promising mechanism for laser controlled drug release in medical applications. We studied the efficiency of such reaction after two-photon excitation, comparing femtosecond and nanosecond pulses in the range from 400 to 800 nm. The photocleavage reaction is remarkably more efficient for shorter wavelengths. The spectral profile of the two-photon absorption (TPA) spectrum resembles the single-photon absorption (SPA) spectrum. It was also observed that the photocleavage reaction triggered with femtosecond pulses is about 4.9 × 10⁴ times more efficient than the reaction with nanosecond pulses at the same wavelength and beam area.

Original language	English
Pages (from-to)	308-312
Number of pages	5
Journal	Chemical Physics Letters
Volume	439
Issue number	4-6
DOIs	https://doi.org/10.1016/j.cplett.2007.03.076
State	Published - 11 May 2007
Externally published	Yes

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title = "The photoinduced cleavage of coumarin dimers studied with femtosecond and nanosecond two-photon excitation",

abstract = "The photocleavage of a coumarin derivative dimer is a promising mechanism for laser controlled drug release in medical applications. We studied the efficiency of such reaction after two-photon excitation, comparing femtosecond and nanosecond pulses in the range from 400 to 800 nm. The photocleavage reaction is remarkably more efficient for shorter wavelengths. The spectral profile of the two-photon absorption (TPA) spectrum resembles the single-photon absorption (SPA) spectrum. It was also observed that the photocleavage reaction triggered with femtosecond pulses is about 4.9 × 104 times more efficient than the reaction with nanosecond pulses at the same wavelength and beam area.",

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T1 - The photoinduced cleavage of coumarin dimers studied with femtosecond and nanosecond two-photon excitation

AU - Buckup, T.

AU - Dorn, J.

AU - Hauer, J.

AU - Härtner, S.

AU - Hampp, N.

AU - Motzkus, M.

PY - 2007/5/11

Y1 - 2007/5/11

N2 - The photocleavage of a coumarin derivative dimer is a promising mechanism for laser controlled drug release in medical applications. We studied the efficiency of such reaction after two-photon excitation, comparing femtosecond and nanosecond pulses in the range from 400 to 800 nm. The photocleavage reaction is remarkably more efficient for shorter wavelengths. The spectral profile of the two-photon absorption (TPA) spectrum resembles the single-photon absorption (SPA) spectrum. It was also observed that the photocleavage reaction triggered with femtosecond pulses is about 4.9 × 104 times more efficient than the reaction with nanosecond pulses at the same wavelength and beam area.

AB - The photocleavage of a coumarin derivative dimer is a promising mechanism for laser controlled drug release in medical applications. We studied the efficiency of such reaction after two-photon excitation, comparing femtosecond and nanosecond pulses in the range from 400 to 800 nm. The photocleavage reaction is remarkably more efficient for shorter wavelengths. The spectral profile of the two-photon absorption (TPA) spectrum resembles the single-photon absorption (SPA) spectrum. It was also observed that the photocleavage reaction triggered with femtosecond pulses is about 4.9 × 104 times more efficient than the reaction with nanosecond pulses at the same wavelength and beam area.

UR - https://www.scopus.com/pages/publications/34247354934

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VL - 439

SP - 308

EP - 312

JO - Chemical Physics Letters

JF - Chemical Physics Letters

IS - 4-6

ER -

The photoinduced cleavage of coumarin dimers studied with femtosecond and nanosecond two-photon excitation

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