TY - JOUR
T1 - The Lumbodorsal Fascia as a Potential Source of Low Back Pain
T2 - A Narrative Review
AU - Wilke, Jan
AU - Schleip, Robert
AU - Klingler, Werner
AU - Stecco, Carla
N1 - Publisher Copyright:
© 2017 Jan Wilke et al.
PY - 2017
Y1 - 2017
N2 - The lumbodorsal fascia (LF) has been proposed to represent a possible source of idiopathic low back pain. In fact, histological studies have demonstrated the presence of nociceptive free nerve endings within the LF, which, furthermore, appear to exhibit morphological changes in patients with chronic low back pain. However, it is unclear how these characteristics relate to the aetiology of the pain. In vivo elicitation of back pain via experimental stimulation of the LF suggests that dorsal horn neurons react by increasing their excitability. Such sensitization of fascia-related dorsal horn neurons, in turn, could be related to microinjuries and/or inflammation in the LF. Despite available data point towards a significant role of the LF in low back pain, further studies are needed to better understand the involved neurophysiological dynamics.
AB - The lumbodorsal fascia (LF) has been proposed to represent a possible source of idiopathic low back pain. In fact, histological studies have demonstrated the presence of nociceptive free nerve endings within the LF, which, furthermore, appear to exhibit morphological changes in patients with chronic low back pain. However, it is unclear how these characteristics relate to the aetiology of the pain. In vivo elicitation of back pain via experimental stimulation of the LF suggests that dorsal horn neurons react by increasing their excitability. Such sensitization of fascia-related dorsal horn neurons, in turn, could be related to microinjuries and/or inflammation in the LF. Despite available data point towards a significant role of the LF in low back pain, further studies are needed to better understand the involved neurophysiological dynamics.
UR - http://www.scopus.com/inward/record.url?scp=85019590935&partnerID=8YFLogxK
U2 - 10.1155/2017/5349620
DO - 10.1155/2017/5349620
M3 - Review article
C2 - 28584816
AN - SCOPUS:85019590935
SN - 2314-6133
VL - 2017
JO - BioMed Research International
JF - BioMed Research International
M1 - 5349620
ER -