The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Frederick W. Kutz; Donald G. Barnes; David P. Bottimore; Helmut Greim; Erich W. Bretthauer

doi:10.1016/0045-6535(90)90178-V

The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Frederick W. Kutz
, Donald G. Barnes
, David P. Bottimore
, Helmut Greim
, Erich W. Bretthauer

US Environmental Protection Agency
Versar Inc.
Helmholtz Zentrum München German Research Center for Environmental Health

Research output: Contribution to journal › Article › peer-review

176 Scopus citations

Abstract

The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

Original language	English
Pages (from-to)	751-757
Number of pages	7
Journal	Chemosphere
Volume	20
Issue number	7-9
DOIs	https://doi.org/10.1016/0045-6535(90)90178-V
State	Published - 1990
Externally published	Yes

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10.1016/0045-6535(90)90178-V

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title = "The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds",

abstract = "The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.",

author = "Kutz, \{Frederick W.\} and Barnes, \{Donald G.\} and Bottimore, \{David P.\} and Helmut Greim and Bretthauer, \{Erich W.\}",

year = "1990",

doi = "10.1016/0045-6535(90)90178-V",

language = "English",

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pages = "751--757",

journal = "Chemosphere",

issn = "0045-6535",

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T1 - The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

AU - Kutz, Frederick W.

AU - Barnes, Donald G.

AU - Bottimore, David P.

AU - Greim, Helmut

AU - Bretthauer, Erich W.

PY - 1990

Y1 - 1990

N2 - The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

AB - The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

UR - https://www.scopus.com/pages/publications/0025061508

U2 - 10.1016/0045-6535(90)90178-V

DO - 10.1016/0045-6535(90)90178-V

M3 - Article

AN - SCOPUS:0025061508

SN - 0045-6535

VL - 20

SP - 751

EP - 757

JO - Chemosphere

JF - Chemosphere

IS - 7-9

ER -

The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Abstract

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