The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Frederick W. Kutz; Donald G. Barnes; David P. Bottimore; Helmut Greim; Erich W. Bretthauer

doi:10.1016/0045-6535(90)90178-V

The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Frederick W. Kutz, Donald G. Barnes, David P. Bottimore, Helmut Greim, Erich W. Bretthauer

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168 Scopus citations

Abstract

The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

Original language	English
Pages (from-to)	751-757
Number of pages	7
Journal	Chemosphere
Volume	20
Issue number	7-9
DOIs	https://doi.org/10.1016/0045-6535(90)90178-V
State	Published - 1990
Externally published	Yes

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title = "The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds",

abstract = "The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.",

author = "Kutz, {Frederick W.} and Barnes, {Donald G.} and Bottimore, {David P.} and Helmut Greim and Bretthauer, {Erich W.}",

year = "1990",

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T1 - The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

AU - Kutz, Frederick W.

AU - Barnes, Donald G.

AU - Bottimore, David P.

AU - Greim, Helmut

AU - Bretthauer, Erich W.

PY - 1990

Y1 - 1990

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AB - The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

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SN - 0045-6535

VL - 20

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EP - 757

JO - Chemosphere

JF - Chemosphere

IS - 7-9

ER -

The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Abstract

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