The international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds

Frederick W. Kutz, Donald G. Barnes, David P. Bottimore, Helmut Greim, Erich W. Bretthauer

Research output: Contribution to journalArticlepeer-review

158 Scopus citations

Abstract

The International Toxicity Equivalency Factor (I-TEF) method of risk assessment is an updated interim procedure for estimating the risks associated with exposures to complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs and CDFs). The I-TEF approach facilitates risk communication internationally by reducing large volumes of analytical data into a single number-International Toxicity Equivalents (I-TEQ). The I-TEF method has been officially adopted in Canada, the Netherlands, the Nordic countries, the United Kingdom, and the United States. As a result, the I-TEF method represents an improvement in an already useful risk assessment/regulatory tool.

Original languageEnglish
Pages (from-to)751-757
Number of pages7
JournalChemosphere
Volume20
Issue number7-9
DOIs
StatePublished - 1990
Externally publishedYes

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