The Influence of Poor Sleep on Quality of Life in Patients with Parkinson's Disease - A Prospective Study

Svenja Happe; Klaus Berger; Wendelin Blersch; Tobias Eichhorn; Thomas Gasser; Bertram Holinka; Stefan Knecht; Andreas Kupsch; Thomas Müller; Volker Riess; Peter Vieregge; Juliane Winkelmann

doi:10.1046/j.1432-9123.2003.00002.x

The Influence of Poor Sleep on Quality of Life in Patients with Parkinson's Disease - A Prospective Study

Svenja Happe, Klaus Berger, Wendelin Blersch, Tobias Eichhorn, Thomas Gasser, Bertram Holinka, Stefan Knecht, Andreas Kupsch, Thomas Müller, Volker Riess, Peter Vieregge, Juliane Winkelmann

Chair of Neurogenetics (2015 — 2023)

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Question of the Study: To assess the associations between sleep complaints and quality of life in patients with Parkinson's disease (PD) prospectively. Design: A prospective German cohort study evaluating determinants of quality of life of PD patients in ambulatory care (FAQT Study) at the neurological outpatient clinics for Parkinson's disease of 10 German university hospitals. Patients and Methods: A group of 111 PD patients was evaluated twice, at baseline and at 1-year follow-up, using standardized and validated questionnaires. Results: At baseline, a third of the PD patients reported poor sleep 3 or more nights a week. Seventy per cent of this group named relevant depressive symptoms, significantly more than in patients with less frequent sleep complaints (P < 0.001). Quality-of-life scores were significantly reduced in patients with frequent poor sleep. Patients with more frequent sleep disturbances at follow-up reported decreased scores of all studied quality-of-life domains, whereas patients with less frequent sleep disturbances reported an improvement in the mental health domain. Conclusion: Sleep problems have an important impact on quality of life in PD patients, also prospectively.

Original language	English
Pages (from-to)	134-139
Number of pages	6
Journal	Somnologie
Volume	7
Issue number	4
DOIs	https://doi.org/10.1046/j.1432-9123.2003.00002.x
State	Published - Nov 2003

Keywords

Depression
Parkinson's disease
Quality of life
Sleep

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1046/j.1432-9123.2003.00002.x

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title = "The Influence of Poor Sleep on Quality of Life in Patients with Parkinson's Disease - A Prospective Study",

abstract = "Question of the Study: To assess the associations between sleep complaints and quality of life in patients with Parkinson's disease (PD) prospectively. Design: A prospective German cohort study evaluating determinants of quality of life of PD patients in ambulatory care (FAQT Study) at the neurological outpatient clinics for Parkinson's disease of 10 German university hospitals. Patients and Methods: A group of 111 PD patients was evaluated twice, at baseline and at 1-year follow-up, using standardized and validated questionnaires. Results: At baseline, a third of the PD patients reported poor sleep 3 or more nights a week. Seventy per cent of this group named relevant depressive symptoms, significantly more than in patients with less frequent sleep complaints (P < 0.001). Quality-of-life scores were significantly reduced in patients with frequent poor sleep. Patients with more frequent sleep disturbances at follow-up reported decreased scores of all studied quality-of-life domains, whereas patients with less frequent sleep disturbances reported an improvement in the mental health domain. Conclusion: Sleep problems have an important impact on quality of life in PD patients, also prospectively.",

keywords = "Depression, Parkinson's disease, Quality of life, Sleep",

author = "Svenja Happe and Klaus Berger and Wendelin Blersch and Tobias Eichhorn and Thomas Gasser and Bertram Holinka and Stefan Knecht and Andreas Kupsch and Thomas M{\"u}ller and Volker Riess and Peter Vieregge and Juliane Winkelmann",

note = "Funding Information: The FAQT Study is supported by the William-Woort-Stiftung f{\"u}r Alternsforschung Essen, Germany and Hoffman LaRoche AG, Germany.",

year = "2003",

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doi = "10.1046/j.1432-9123.2003.00002.x",

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T1 - The Influence of Poor Sleep on Quality of Life in Patients with Parkinson's Disease - A Prospective Study

AU - Happe, Svenja

AU - Berger, Klaus

AU - Blersch, Wendelin

AU - Eichhorn, Tobias

AU - Gasser, Thomas

AU - Holinka, Bertram

AU - Knecht, Stefan

AU - Kupsch, Andreas

AU - Müller, Thomas

AU - Riess, Volker

AU - Vieregge, Peter

AU - Winkelmann, Juliane

N1 - Funding Information: The FAQT Study is supported by the William-Woort-Stiftung für Alternsforschung Essen, Germany and Hoffman LaRoche AG, Germany.

PY - 2003/11

Y1 - 2003/11

N2 - Question of the Study: To assess the associations between sleep complaints and quality of life in patients with Parkinson's disease (PD) prospectively. Design: A prospective German cohort study evaluating determinants of quality of life of PD patients in ambulatory care (FAQT Study) at the neurological outpatient clinics for Parkinson's disease of 10 German university hospitals. Patients and Methods: A group of 111 PD patients was evaluated twice, at baseline and at 1-year follow-up, using standardized and validated questionnaires. Results: At baseline, a third of the PD patients reported poor sleep 3 or more nights a week. Seventy per cent of this group named relevant depressive symptoms, significantly more than in patients with less frequent sleep complaints (P < 0.001). Quality-of-life scores were significantly reduced in patients with frequent poor sleep. Patients with more frequent sleep disturbances at follow-up reported decreased scores of all studied quality-of-life domains, whereas patients with less frequent sleep disturbances reported an improvement in the mental health domain. Conclusion: Sleep problems have an important impact on quality of life in PD patients, also prospectively.

AB - Question of the Study: To assess the associations between sleep complaints and quality of life in patients with Parkinson's disease (PD) prospectively. Design: A prospective German cohort study evaluating determinants of quality of life of PD patients in ambulatory care (FAQT Study) at the neurological outpatient clinics for Parkinson's disease of 10 German university hospitals. Patients and Methods: A group of 111 PD patients was evaluated twice, at baseline and at 1-year follow-up, using standardized and validated questionnaires. Results: At baseline, a third of the PD patients reported poor sleep 3 or more nights a week. Seventy per cent of this group named relevant depressive symptoms, significantly more than in patients with less frequent sleep complaints (P < 0.001). Quality-of-life scores were significantly reduced in patients with frequent poor sleep. Patients with more frequent sleep disturbances at follow-up reported decreased scores of all studied quality-of-life domains, whereas patients with less frequent sleep disturbances reported an improvement in the mental health domain. Conclusion: Sleep problems have an important impact on quality of life in PD patients, also prospectively.

KW - Depression

KW - Parkinson's disease

KW - Quality of life

KW - Sleep

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The Influence of Poor Sleep on Quality of Life in Patients with Parkinson's Disease - A Prospective Study

Abstract

Keywords

UN SDGs

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