The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis

R. D. O'CONNOR; J. RING; A. A. JALOWAYSKI; R. N. HAMBURGER

doi:10.1111/j.1365-2222.1980.tb02155.x

The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis

R. D. O'CONNOR
, J. RING
, A. A. JALOWAYSKI
, R. N. HAMBURGER

Scripps Research Institute

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The in vitro effect of levamisole (LMS) on lymphocyte, neutrophil, basophil and platelet function was investigated in patients with severe atopic dermatitis and hyper‐immunoglobulinaemia E. Lymphocyte stimulation by several concentrations of PHA, con A and PWM, polymorphonuclear leukocyte chemotaxis and basophil histamine release were unaffected by LMS (10 μg/ml). Platelet serotonin release induced by iodipamide was decreased in patient and control groups by LMS but release induced by methacholine, epinephrine and thrombin was not.

Original language	English
Pages (from-to)	705-713
Number of pages	9
Journal	Clinical and Experimental Allergy
Volume	10
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2222.1980.tb02155.x
State	Published - Nov 1980
Externally published	Yes

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O'CONNOR, R. D., RING, J., JALOWAYSKI, A. A., & HAMBURGER, R. N. (1980). The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis. Clinical and Experimental Allergy, 10(6), 705-713. https://doi.org/10.1111/j.1365-2222.1980.tb02155.x

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abstract = "The in vitro effect of levamisole (LMS) on lymphocyte, neutrophil, basophil and platelet function was investigated in patients with severe atopic dermatitis and hyper‐immunoglobulinaemia E. Lymphocyte stimulation by several concentrations of PHA, con A and PWM, polymorphonuclear leukocyte chemotaxis and basophil histamine release were unaffected by LMS (10 μg/ml). Platelet serotonin release induced by iodipamide was decreased in patient and control groups by LMS but release induced by methacholine, epinephrine and thrombin was not.",

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year = "1980",

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doi = "10.1111/j.1365-2222.1980.tb02155.x",

language = "English",

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O'CONNOR, RD, RING, J, JALOWAYSKI, AA & HAMBURGER, RN 1980, 'The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis', Clinical and Experimental Allergy, vol. 10, no. 6, pp. 705-713. https://doi.org/10.1111/j.1365-2222.1980.tb02155.x

The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis. / O'CONNOR, R. D.; RING, J.; JALOWAYSKI, A. A. et al.
In: Clinical and Experimental Allergy, Vol. 10, No. 6, 11.1980, p. 705-713.

Research output: Contribution to journal › Article › peer-review

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AU - JALOWAYSKI, A. A.

AU - HAMBURGER, R. N.

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AB - The in vitro effect of levamisole (LMS) on lymphocyte, neutrophil, basophil and platelet function was investigated in patients with severe atopic dermatitis and hyper‐immunoglobulinaemia E. Lymphocyte stimulation by several concentrations of PHA, con A and PWM, polymorphonuclear leukocyte chemotaxis and basophil histamine release were unaffected by LMS (10 μg/ml). Platelet serotonin release induced by iodipamide was decreased in patient and control groups by LMS but release induced by methacholine, epinephrine and thrombin was not.

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ER -

The in vitro effect of levamisole on lymphocyte proliferation, polymorphonuclear leucocyte chemotaxis, basophil histamine release and platelet serotonin release in patients with atopic dermatitis

Abstract

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