The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals

Marc Hinderer; Martin Boeker; Sebastian A. Wagner; Harald Binder; Frank Ückert; Stephanie Newe; Jan L. Hülsemann; Michael Neumaier; Carmen Schade-Brittinger; Till Acker; Hans Ulrich Prokosch; Brita Sedlmayr

doi:10.2217/pgs-2017-0027

The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals

Marc Hinderer, Martin Boeker, Sebastian A. Wagner, Harald Binder, Frank Ückert, Stephanie Newe, Jan L. Hülsemann, Michael Neumaier, Carmen Schade-Brittinger, Till Acker, Hans Ulrich Prokosch, Brita Sedlmayr

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Aim: The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals. Materials & methods: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed. Results: The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists. Conclusion: Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.

Original language	English
Pages (from-to)	773-785
Number of pages	13
Journal	Pharmacogenomics
Volume	18
Issue number	8
DOIs	https://doi.org/10.2217/pgs-2017-0027
State	Published - Jun 2017
Externally published	Yes

Keywords

German university hospital
clinical decision support
pharmacogenomic

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10.2217/pgs-2017-0027

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Hinderer, M., Boeker, M., Wagner, S. A., Binder, H., Ückert, F., Newe, S., Hülsemann, J. L., Neumaier, M., Schade-Brittinger, C., Acker, T., Prokosch, H. U., & Sedlmayr, B. (2017). The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals. Pharmacogenomics, 18(8), 773-785. https://doi.org/10.2217/pgs-2017-0027

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abstract = "Aim: The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals. Materials & methods: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed. Results: The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists. Conclusion: Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.",

keywords = "German university hospital, clinical decision support, pharmacogenomic",

author = "Marc Hinderer and Martin Boeker and Wagner, {Sebastian A.} and Harald Binder and Frank {\"U}ckert and Stephanie Newe and H{\"u}lsemann, {Jan L.} and Michael Neumaier and Carmen Schade-Brittinger and Till Acker and Prokosch, {Hans Ulrich} and Brita Sedlmayr",

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year = "2017",

month = jun,

doi = "10.2217/pgs-2017-0027",

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AU - Hinderer, Marc

AU - Boeker, Martin

AU - Wagner, Sebastian A.

AU - Binder, Harald

AU - Ückert, Frank

AU - Newe, Stephanie

AU - Hülsemann, Jan L.

AU - Neumaier, Michael

AU - Schade-Brittinger, Carmen

AU - Acker, Till

AU - Prokosch, Hans Ulrich

AU - Sedlmayr, Brita

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AB - Aim: The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals. Materials & methods: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. In total, 564 returned questionnaires were analyzed. Results: The remaining knowledge gap, the uncertainty of test reimbursement and the physicians' lack of awareness of existing pharmacogenomic clinical decision support systems (CDSS) are the major barriers for implementing pharmacogenomic CDSS into German hospitals. Furthermore, pharmacogenomic CDSS are most effective in the form of real-time decision support for internists. Conclusion: Physicians in German hospitals require additional education of both genetics and pharmacogenomics. They need to be provided with access to relevant pharmacogenomic CDSS.

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ER -

The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals

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Keywords

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