TY - JOUR
T1 - The controversial linear no-Threshold model
AU - Weber, Wolfgang
AU - Zanzonico, Pat
N1 - Publisher Copyright:
© COPYRIGHT 2017 by the Society of Nuclear Medicine and Molecular Imaging.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Estimating the risk of cancer induction by low-dose radiation (e.g., diagnostic) remains one of the most contentious issues in modern science and has engendered often-strident debate (1,2), particularly with respect to the linear no-Threshold (LNT) dose-response model. As John Boice, Jr., president of the National Council on Radiation Protection and Measurements (NCRP), has aptly stated (3), "LNT is not TNT, but differences in opinions sometimes appear explosive!" A critical assessment of the LNT model and a consideration of alternative dose-response models are presented in the article by Siegel, Pennington, and Sacks in this issue of The Journal of Nuclear Medicine (3). The article highlights the uncertainty associated with the LNT model and LNT model-based risk factors.
AB - Estimating the risk of cancer induction by low-dose radiation (e.g., diagnostic) remains one of the most contentious issues in modern science and has engendered often-strident debate (1,2), particularly with respect to the linear no-Threshold (LNT) dose-response model. As John Boice, Jr., president of the National Council on Radiation Protection and Measurements (NCRP), has aptly stated (3), "LNT is not TNT, but differences in opinions sometimes appear explosive!" A critical assessment of the LNT model and a consideration of alternative dose-response models are presented in the article by Siegel, Pennington, and Sacks in this issue of The Journal of Nuclear Medicine (3). The article highlights the uncertainty associated with the LNT model and LNT model-based risk factors.
UR - http://www.scopus.com/inward/record.url?scp=85009075012&partnerID=8YFLogxK
U2 - 10.2967/jnumed.116.182667
DO - 10.2967/jnumed.116.182667
M3 - Review article
C2 - 27754908
AN - SCOPUS:85009075012
SN - 0161-5505
VL - 58
SP - 7
EP - 8
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
IS - 1
ER -