The binding of sulfate anions by guanidinium receptors is entropy-driven

Michael Berger; Franz P. Schmidtchen

doi:10.1002/(SICI)1521-3773(19981016)37:19<2694::AID-ANIE2694>3.0.CO;2-Q

The binding of sulfate anions by guanidinium receptors is entropy-driven

Michael Berger, Franz P. Schmidtchen

Natural Sciences

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

Clear trends in the molecular recognition of guest species by artificial hosts in solution are often observed by intrinsic enthalpy-entropy compensation, which requires the dissection of these free-energy components. Contrary to common belief, it is not the enthalpic electrostatic attraction that makes guanidinium hosts such as 1 strong binders for sulfate anions. Isothermal titration calorimetry has now allowed this molecular recognition to be characterized as an entropy-driven association.

Original language	English
Pages (from-to)	2694-2696
Number of pages	3
Journal	Angewandte Chemie International Edition in English
Volume	37
Issue number	19
DOIs	https://doi.org/10.1002/(SICI)1521-3773(19981016)37:19<2694::AID-ANIE2694>3.0.CO;2-Q
State	Published - 16 Oct 1998

Keywords

Calorimetry
Guanidine
Host-guest chemistry
Thermodynamics

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10.1002/(SICI)1521-3773(19981016)37:19<2694::AID-ANIE2694>3.0.CO;2-Q

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KW - Calorimetry

KW - Guanidine

KW - Host-guest chemistry

KW - Thermodynamics

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The binding of sulfate anions by guanidinium receptors is entropy-driven

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Keywords

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