The backbone dynamics of the amyloid precursor protein transmembrane helix provides a rationale for the sequential cleavage mechanism of γ-secretase

Oxana Pester, Paul J. Barrett, Daniel Hornburg, Philipp Hornburg, Rasmus Pröbstle, Simon Widmaier, Christoph Kutzner, Milena Dürrbaum, Aphrodite Kapurniotu, Charles R. Sanders, Christina Scharnagl, Dieter Langosch

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Biochemistry, Genetics and Molecular Biology