Abstract
There has been clinical evidence that a perfusion defect on a stress image fills in over time. The diagnostic value of initial and 120 min post exercise redistribution thallium-201 myocardial images (RMI) was determined in 120 pts. with suspected coronary heart disease (CAD), all of whom had coronary arteriography. Significant (≥75%) lesions were present in 88 pts. 30 pts. without CAD showed a normal tracer uptake immediately after exercise. Scintigrams taken 120 min after exercise revealed a decrease of 201-Tl concentration in every area of the myocardium. 80 pts. with CAD showed an area of decreased tracer uptake in the initial scans. 120 min RMI in 51 pts. revealed a significant increase (p>0.01) of countrate time ratio in previous underperfused areas. In 37 pts. persistent defects were present, in every case the defects correlated with the site of a myocardial infarction as determined by the finding of an akinetic area in the left ventricuar angiogram. Thus RMI following a single dose of 201 Tl can differentiate between scar- and exercise-induced transient ischemia.
Translated title of the contribution | Value of 201-Thallium serial myocardial imaging in coronary heart disease |
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Original language | German |
Pages (from-to) | 454-460 |
Number of pages | 7 |
Journal | Zeitschrift fur Kardiologie |
Volume | 68 |
Issue number | 7 |
State | Published - 1979 |