Tetrabromobisphenol A

Helmut Greim

doi:10.1016/B978-0-12-824315-2.00323-7

Tetrabromobisphenol A

Helmut Greim

Default

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Tetrabromobisphenol A (TBBPA) is primarily used as a reactive flame retardant in epoxy resin circuit boards. TBBPA is also used in polycarbonate and ether polyester resins and is used as a flame retardant in plastics, paper, and textiles, and as a plasticizer in adhesives and coatings. Being covalently bound to the polymer limits the exposure to unbound excess chemical used in the manufacturing process. TBBPA demonstrates relatively low acute toxicity and effects seem to be mediated by interactions with membranes. Chronic studies suggest some potential for immunological or porphyrogenic activity. According to long-term studies in rats and mice IARC has classified TBBPA as probably carcinogenic to humans (Group 2A).

Original language	English
Title of host publication	Encyclopedia of Toxicology, Fourth Edition
Subtitle of host publication	Volume 1-9
Publisher	Elsevier
Pages	V8-971-V8-975
Volume	8
ISBN (Electronic)	9780128243152
DOIs	https://doi.org/10.1016/B978-0-12-824315-2.00323-7
State	Published - 1 Jan 2023

Keywords

Ah receptor
Bioconcentration
Endocrine
Estrogenic
Flame retardant
Immunotoxicity
Membrane effects
Photodegradation
Porphyria

Access to Document

10.1016/B978-0-12-824315-2.00323-7

Cite this

@inbook{27ae9c0ed6e843f6924a0550c500f040,

title = "Tetrabromobisphenol A",

abstract = "Tetrabromobisphenol A (TBBPA) is primarily used as a reactive flame retardant in epoxy resin circuit boards. TBBPA is also used in polycarbonate and ether polyester resins and is used as a flame retardant in plastics, paper, and textiles, and as a plasticizer in adhesives and coatings. Being covalently bound to the polymer limits the exposure to unbound excess chemical used in the manufacturing process. TBBPA demonstrates relatively low acute toxicity and effects seem to be mediated by interactions with membranes. Chronic studies suggest some potential for immunological or porphyrogenic activity. According to long-term studies in rats and mice IARC has classified TBBPA as probably carcinogenic to humans (Group 2A).",

keywords = "Ah receptor, Bioconcentration, Endocrine, Estrogenic, Flame retardant, Immunotoxicity, Membrane effects, Photodegradation, Porphyria",

author = "Helmut Greim",

year = "2023",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-824315-2.00323-7",

language = "English",

volume = "8",

pages = "V8--971--V8--975",

booktitle = "Encyclopedia of Toxicology, Fourth Edition",

publisher = "Elsevier",

}

TY - CHAP

T1 - Tetrabromobisphenol A

AU - Greim, Helmut

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Tetrabromobisphenol A (TBBPA) is primarily used as a reactive flame retardant in epoxy resin circuit boards. TBBPA is also used in polycarbonate and ether polyester resins and is used as a flame retardant in plastics, paper, and textiles, and as a plasticizer in adhesives and coatings. Being covalently bound to the polymer limits the exposure to unbound excess chemical used in the manufacturing process. TBBPA demonstrates relatively low acute toxicity and effects seem to be mediated by interactions with membranes. Chronic studies suggest some potential for immunological or porphyrogenic activity. According to long-term studies in rats and mice IARC has classified TBBPA as probably carcinogenic to humans (Group 2A).

AB - Tetrabromobisphenol A (TBBPA) is primarily used as a reactive flame retardant in epoxy resin circuit boards. TBBPA is also used in polycarbonate and ether polyester resins and is used as a flame retardant in plastics, paper, and textiles, and as a plasticizer in adhesives and coatings. Being covalently bound to the polymer limits the exposure to unbound excess chemical used in the manufacturing process. TBBPA demonstrates relatively low acute toxicity and effects seem to be mediated by interactions with membranes. Chronic studies suggest some potential for immunological or porphyrogenic activity. According to long-term studies in rats and mice IARC has classified TBBPA as probably carcinogenic to humans (Group 2A).

KW - Ah receptor

KW - Bioconcentration

KW - Endocrine

KW - Estrogenic

KW - Flame retardant

KW - Immunotoxicity

KW - Membrane effects

KW - Photodegradation

KW - Porphyria

UR - http://www.scopus.com/inward/record.url?scp=85188049713&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-824315-2.00323-7

DO - 10.1016/B978-0-12-824315-2.00323-7

M3 - Chapter

AN - SCOPUS:85188049713

VL - 8

SP - V8-971-V8-975

BT - Encyclopedia of Toxicology, Fourth Edition

PB - Elsevier

ER -

Tetrabromobisphenol A

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this