Taxonomic distribution of plant glutathione S-transferases acting on xenobiotics

Stephan Pflugmacher, Peter Schröder, Heinrich Sandermann

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

Soluble and microsomal glutathione S-transferase activities for five model xenobiotics (nitrobenzene derivatives), two pesticidal xenobiotics (atrazine and fluorodifen), and a natural substrate (cinnamic acid), were determined in 59 different plant species and four plant cell suspension cultures. These enzyme activities were widely distributed over the plant kingdom with certain species showing particularly high activities. Marine macroalgae had a remarkably broad substrate range that included the substrates atrazine and fluorodifen. It is concluded that the evolutionary 'green liver' concept derived for xenobiotic metabolism in higher plant species is also valid for the constitutive soluble and microsomal glutathione S-transferases of lower plant species. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)267-273
Number of pages7
JournalPhytochemistry
Volume54
Issue number3
DOIs
StatePublished - 1 Jun 2000
Externally publishedYes

Keywords

  • CDNB, 1-chloro-2,4-dinitrobenzene
  • DCNB, 1,2-dichloro-4- nitrobenzene
  • EPNP, 1,2-epoxy-3-(4-nitrophenoxy)-propane
  • GSH, glutathione
  • GST, glutathione S-transferase
  • IDNB, 1-iodo-2,4-dinitrobenzene
  • pNBC, 4- nitrobenzoylchloride

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