Systemische therapie des fortgeschrittenen urothelkarzinoms

J. Lehmann; M. Retz; M. Stöckle

doi:10.1007/s00761-005-0970-x

Systemische therapie des fortgeschrittenen urothelkarzinoms

Translated title of the contribution: Systemic chemotherapy for advanced urothelial carcinoma

J. Lehmann, M. Retz, M. Stöckle

Saarland University

Research output: Contribution to journal › Review article › peer-review

Abstract

Moderate activity of single-agent systemic chemotherapy for advanced urothelial cancer has been reported for more than 30 years. With the introduction of potent combination therapy in the mid-1980s, a clinically significant rate of response as well as prolonged survival was achieved. This review summarizes the results of phase III trials of palliative systemic chemotherapy for advanced urothelial carcinoma as well as recent data from adjuvant and neoadjuvant trials for muscle-invasive bladder cancer.

Translated title of the contribution	Systemic chemotherapy for advanced urothelial carcinoma
Original language	German
Pages (from-to)	1210-1218
Number of pages	9
Journal	Onkologe
Volume	11
Issue number	11
DOIs	https://doi.org/10.1007/s00761-005-0970-x
State	Published - Nov 2005
Externally published	Yes

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abstract = "Moderate activity of single-agent systemic chemotherapy for advanced urothelial cancer has been reported for more than 30 years. With the introduction of potent combination therapy in the mid-1980s, a clinically significant rate of response as well as prolonged survival was achieved. This review summarizes the results of phase III trials of palliative systemic chemotherapy for advanced urothelial carcinoma as well as recent data from adjuvant and neoadjuvant trials for muscle-invasive bladder cancer.",

keywords = "Adjuvant chemotherapy, Bladder cancer, Neoadjuvant chemotherapy, Systemic chemotherapy, Transitional cell carcinoma",

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doi = "10.1007/s00761-005-0970-x",

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AU - Retz, M.

AU - Stöckle, M.

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N2 - Moderate activity of single-agent systemic chemotherapy for advanced urothelial cancer has been reported for more than 30 years. With the introduction of potent combination therapy in the mid-1980s, a clinically significant rate of response as well as prolonged survival was achieved. This review summarizes the results of phase III trials of palliative systemic chemotherapy for advanced urothelial carcinoma as well as recent data from adjuvant and neoadjuvant trials for muscle-invasive bladder cancer.

AB - Moderate activity of single-agent systemic chemotherapy for advanced urothelial cancer has been reported for more than 30 years. With the introduction of potent combination therapy in the mid-1980s, a clinically significant rate of response as well as prolonged survival was achieved. This review summarizes the results of phase III trials of palliative systemic chemotherapy for advanced urothelial carcinoma as well as recent data from adjuvant and neoadjuvant trials for muscle-invasive bladder cancer.

KW - Adjuvant chemotherapy

KW - Bladder cancer

KW - Neoadjuvant chemotherapy

KW - Systemic chemotherapy

KW - Transitional cell carcinoma

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ER -

Systemische therapie des fortgeschrittenen urothelkarzinoms

Abstract

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